This book constitutes the refereed proceedings of the 7th International Conference on Computer, Communication, and Signal Processing, ICCCSP 2023, held in Chennai, India, during January 4–6, 2023, in hybrid mode. The 17 full and 9 short papers presented in this volume were carefully reviewed and selected from 123 submissions. The papers are categorized into topical sections: artificial intelligence in health care; machine learning and deep learning; signal processing; and Internet of Things for smart systems.